![]() Thereafter, continued anticoagulant therapy for secondary prevention is indicated in selected patients to reduce the risk of recurrent events. ![]() Generally, anticoagulant therapy for at least 3 months is required for patients with DVT. Interventional therapies, including thrombolysis, are rarely indicated. DVT may also be unprovoked (idiopathic) and occur in the absence of any identifiable extrinsic risk factors.ĭVTs commonly cause asymmetrical leg swelling, unilateral leg pain, dilation or distension of superficial veins, and red or discolored skin, but can also be asymptomatic.Īssessment of pre-test probability (using a validated score such as Wells) is key if DVT is suspected, and should be used in combination with an algorithmic diagnostic approach to avoid unnecessary imaging when the likelihood of DVT is low.ĭiagnosis requires confirmation of a blood clot in a deep vein in the leg, pelvis, or vena cava by venous ultrasound imaging (or other imaging techniques such as computed tomography scan).ĭVT is usually treated with anticoagulants such as unfractionated heparin, low molecular weight heparin, fondaparinux, rivaroxaban, apixaban, edoxaban, dabigatran, and/or warfarin. Patients who develop DVT commonly have risk factors, such as active cancer, trauma, major surgery, hospitalisation, immobilisation, pregnancy, or oral contraceptive use. Deep vein thrombosis (DVT) is the development of a blood clot within a vein deep to the muscular tissue planes.
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